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The Sexual Effectiveness of
Plant Extracts
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Scientific studies have demonstrated the effectiveness of
certain plant extracts in facilitating penis erection.
Phytomedicine. 2003 Nov;10(8):669-74.
Argentinian plant extracts with relaxant
effect on the smooth muscle of the corpus cavernosum of guinea pig.
·
Hnatyszyn O,
·
Moscatelli V,
·
Garcia J,
·
Rondina R,
·
Costa M,
·
Arranz C,
·
Balaszczuk A,
·
Ferraro G,
·
Coussio JD.
Catedra de Farmacognosia,
IQUIMEFA (UBA-CONICET), Facultad de Farmacia y Bioquimica, Universidad
de Buenos Aires,Buenos
Aires, Argentina. ohnatys@ffyb.uba.ar
Extracts of different
polarity from Baccharis trimera, Haplopappus rigidus Huperzia saururus,
Maytenus ilicifolia, Satureja parvifolia and Senecio eriophyton were
tested for their relaxant activity on smooth muscle using L-
phenylephrine
precontracted strips of corpus cavernosum obtained from Guinea pigs.
Highly significant and dose dependent results were
obtained with the
dichloromethane extracts of H. saururus (87% of relaxation at the dose
of 10 mg/ml), S. parvifolia (95% of relaxation at
2.5 mg/ml) and S. eriophyton (94% of relaxation at 5 mg/ml). Similar effects were observed
with the methanol extracts of H. saururus
(88% of relaxation at 10
mg/ml) and S. parvifolia (84% of relaxation at 10 mg/ml). These results
were comparable to those obtained with
the dichloromethane and methanol
extracts of the well known Mexican species Turnera diffusa. Moreover,
the aqueous extract of H.
rigidus and the aqueous and methanol extracts
of S. eriophyton were highly effective in a dose dependent manner (more
than 90% of
relaxation at the dose of 10 mg/ml). Significant results,
but with a lower overall relaxant activity (about 70% of relaxation at
10 mg/ml),
could also be obtained with the aqueous extract of S. parvifolia and with the dichlormethane and methanol extracts of B.
trimera and M.
ilicifolia. The positive controls with Sildenafil citrate
at doses ranging from 0.35 to 35 microg/ml yielded moderate effects (up
to 46% of
relaxation at 35 microg/ml). The
effects observed in the present study seem to validate the folk
medicinal use of the tested
plants and open new ways in the search for
natural products with vasodilatory effects.
PMID: 14692728 [PubMed -
indexed for MEDLINE]
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