Herbal Remedy Reduces Obesity And Heart Disease
Science Daily (July 8, 2008) — With
unprecedented levels of obesity across the Western world, and incidence of
associated heart disease, cancer and diabetes rising, there is a major drive
to find new treatments. Scientists from Germany have recently discovered
that extracts of a traditional herbal remedy derived from Tabebuia
impetiginosa can act to delay the absorption of dietary fat in animal
models.
They believe that the extract could be incorporated into a food
supplement which may not only reduce obesity, but also lessen the risk of
development of type 2 diabetes and coronary heart disease. Dr Nils Roos from
the Max Rubner Institute will present the results on July 7th at the Society
for Experimental Biology's Annual Meeting in Marseille.
Tabebuia impetiginosa, commonly known as Pink Ipê, is a deciduous tree,
native to Central and South America, and is related to magnolias.
Dr Roos and his team have shown that Tabebuia extract can reduce levels
of triglycerides, a breakdown product of fat, in rats after they have been
fed a fatty meal. "This result shows the extract may have a potential use in
treating obesity," he observes.
"However, as coronary heart disease and diabetes have also been shown to
be associated with higher triglyceride levels after eating, we believe a
food-supplement based on Tabebuia could reduce the incidence of these
diseases as well. What is more, as obesity in developing countries is also
on the increase, such extracts, taken as a capsule or added to food, may be
a cheaper alternative for the rural population to pharmaceuticals, he
continued."
Although it is clear that Tabebuia extract can act to inhibit the
absorption of dietary fat, the scientists have not yet identified the exact
compounds within the extract that are responsible for the effects. "The
actual substances involved are probably even more active than the extract,"
says Dr Roos. "We are currently in the process of identifying these
compounds, and will then test long-term efficacy and safety in miniature
pigs whose physiology is closer to that of humans than rat physiology is,
before moving onto human trials. At this point, we hope to be able to
develop the extract, either as a food supplement or in a medicinal context."
Journal reference:
1.
Möller, N. P., Roos, N., Schrezenmeir, J. Lipase inhibitory
activity in alcoholic extracts of worldwide occurring plants and propolis.
Phytotherapy Research, (in press)
Society for Experimental Biology (2008, July 8). Herbal
Remedy Reduces Obesity And Heart Disease?. ScienceDaily. Retrieved
July 10, 2008, from http://www.sciencedaily.com
/releases/2008/07/080707102903.htm
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