The Side Effects of Some Prescription Drugs You Take May
Be to Reduce Testosterone and Cause Erectile Dysfunction
Be sure you research all of the side effects of each prescription drug you
take to learn if any reduce testosterone levels and/or cause erectile
dysfunction. Type in the precise scientific name (and separately also
research the brand name you take) for each drug you regularly take into a
Google search in conjunction with the words testosterone and erectile
dysfunction.
For example, the drugs ketoconazole
and itraconazole (Sporanox) are widely prescribed by physicians for fungal
infections of the skin, nails, and elsewhere in the body. When you do Google
searches for ketoconazole testosterone, ketoconazole erectile dysfunction,
itraconazole testosterone, and ketoconazole erectile dysfunction, you will
discover that both medications are very effective blockers of testosterone
and causes of erectile dysfunction. Fortunately, the cessation of the use of
either drug enables normal testosterone and erection functions to return to
normal.
Psychotropic drug-induced sexual function disorders:
diagnosis, incidence and management
by
Clayton DO, Shen WW
Department of Psychiatry,
St Louis University School of Medicine,
Missouri 63104, USA.
Drug Saf 1998 Oct; 19(4):299-312
ABSTRACT
The human sexual response can be divided into 3
phases: desire (libido), excitement (arousal) and orgasm. The fourth
edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-IV) classifies sexual disorders into 4 categories: (i) primary; (ii)
general medical condition-related; (iii) substance-induced; and (iv) 'not
otherwise specified' sexual dysfunctions. Each of the 4 DSM-IV categories
has disorders in all 3 sexual phases. Substance-induced sexual
dysfunctions are caused by the use of either substances of abuse [alcohol
(ethanol), amphetamines, cocaine, opioids or sedatives/hypnotics/anxiolytics],
or prescription medications which include psychotropic drugs. Patients
with psychiatric difficulties tend to experience more frequent sexual
function disturbances. The literature provides more than anecdotal
evidence that psychotropic drugs can induce sexual function disorders in
the epidemiologically vulnerable population of psychiatric patients.
Sexual dysfunctions caused by psychotropic drugs can be divided into 2
groups: sexual inhibition (inhibited desire, inhibited arousal and
inhibited orgasm) and increased sexual function disorders (increased
sexual desire, priapism and premature ejaculation). The diagnosis of
psychotropic drug-induced sexual function disorders is easy if the
psychiatrist is sensitive to the existence of these adverse effects. This
mostly involves careful history taking, although several questionnaires
have been developed for reliable and valid quantification of sexual
functioning. Diagnosis is usually established if the sexual function
disorders develop when the patient is receiving a psychotropic drug and
then disappear when the offending drug is discontinued. The management of
psychotropic-drug induced sexual inhibition can be divided into 6 steps:
inform the patient about the possibility of sexual inhibition occurring
before prescribing a psychotropic agent; wait for remission or tolerance
of sexual inhibition; reduce the dosage of the psychotropic drug; switch
the medication to one less likely to cause sexual inhibition; if possible,
adjust the concomitant nonpsychotropic drugs; and add various
pharmacological agents to the existing psychotropic drug to treat the
sexual inhibition. Physicians should take sexual histories as a routine
practice when prescribing psychotropic drugs. Through careful management
and patience on the part of both the patient and the physician,
psychotropic drug-induced sexual function disorders can be improved so
that the patient's compliance with medication and quality of life can be
optimised.
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