Drug-Iinduced-Sexual-Disorders

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The Side Effects of Some Prescription Drugs You Take May Be
       to Reduce Testosterone and Cause Erectile Dysfunction

        Be sure you research all of the side effects of each prescription drug you take to learn if any reduce testosterone levels and/or cause erectile dysfunction. Type in the precise scientific name (and separately also research the brand name you take) for each drug you regularly take into a Google search in conjunction with the words testosterone and erectile dysfunction.

        For example, the drugs ketoconazole and itraconazole (Sporanox) are widely prescribed by physicians for fungal infections of the skin, nails, and elsewhere in the body. When you do Google searches for ketoconazole testosterone, ketoconazole erectile dysfunction, itraconazole testosterone, and ketoconazole erectile dysfunction, you will discover that both medications are very effective blockers of testosterone and causes of erectile dysfunction. Fortunately, the cessation of the use of either drug enables normal testosterone and erection functions to return to normal.

         Psychotropic drug-induced sexual function disorders:
                      diagnosis, incidence and management
                                                               by
                                                               Clayton DO, Shen WW
                                                               Department of Psychiatry,
                                                               St Louis University School of Medicine,
                                                              Missouri 63104, USA.
                                                              Drug Saf 1998 Oct; 19(4):299-312

ABSTRACT

The human sexual response can be divided into 3 phases: desire (libido), excitement (arousal) and orgasm. The fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) classifies sexual disorders into 4 categories: (i) primary; (ii) general medical condition-related; (iii) substance-induced; and (iv) 'not otherwise specified' sexual dysfunctions. Each of the 4 DSM-IV categories has disorders in all 3 sexual phases. Substance-induced sexual dysfunctions are caused by the use of either substances of abuse [alcohol (ethanol), amphetamines, cocaine, opioids or sedatives/hypnotics/anxiolytics], or prescription medications which include psychotropic drugs. Patients with psychiatric difficulties tend to experience more frequent sexual function disturbances. The literature provides more than anecdotal evidence that psychotropic drugs can induce sexual function disorders in the epidemiologically vulnerable population of psychiatric patients. Sexual dysfunctions caused by psychotropic drugs can be divided into 2 groups: sexual inhibition (inhibited desire, inhibited arousal and inhibited orgasm) and increased sexual function disorders (increased sexual desire, priapism and premature ejaculation). The diagnosis of psychotropic drug-induced sexual function disorders is easy if the psychiatrist is sensitive to the existence of these adverse effects. This mostly involves careful history taking, although several questionnaires have been developed for reliable and valid quantification of sexual functioning. Diagnosis is usually established if the sexual function disorders develop when the patient is receiving a psychotropic drug and then disappear when the offending drug is discontinued. The management of psychotropic-drug induced sexual inhibition can be divided into 6 steps: inform the patient about the possibility of sexual inhibition occurring before prescribing a psychotropic agent; wait for remission or tolerance of sexual inhibition; reduce the dosage of the psychotropic drug; switch the medication to one less likely to cause sexual inhibition; if possible, adjust the concomitant nonpsychotropic drugs; and add various pharmacological agents to the existing psychotropic drug to treat the sexual inhibition. Physicians should take sexual histories as a routine practice when prescribing psychotropic drugs. Through careful management and patience on the part of both the patient and the physician, psychotropic drug-induced sexual function disorders can be improved so that the patient's compliance with medication and quality of life can be optimised.

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