ScienceDaily (July 31, 2008) —
An enriched extract of the 'Indian Frankincense' herb Boswellia serrata
has been proven to reduce the symptoms of osteoarthritis. Research
published today in BioMed Central's open access journal Arthritis
Research & Therapy has shown that patients taking the herbal remedy
showed significant improvement in as little as seven days.
Osteoarthritis is the most common form of arthritis; it commonly
affects weight-bearing joints such as the knees and hips, along with the
hands, wrists, feet and spine. The symptoms include pain, stiffness and
limited movement. This randomised, double-blinded, placebo-controlled
trial of 70 patients will be of great interest to sufferers, especially
those who don't get adequate relief from existing treatments.
The study was led by Siba Raychaudhuri, a faculty member of the
University of California, Davis, in the United States. According to
Raychaudhuri, "The high incidence of adverse affects associated with
currently available medications has created great interest in the search
for an effective and safe alternative treatment". The extract the
authors used was enriched with 30% AKBA
(3-O-acetyl-11-keto-beta-boswellic acid), which is thought to be the
most active ingredient in the plant. Raychaudhuri said, "AKBA has
anti-inflammatory properties, and we have shown that B. serrata enriched
with AKBA can be an effective treatment for osteoarthritis of the knee".
This is a proprietary product developed by Laila Nutraceuticals.
B. serrata has been used for thousands of years in the Indian system
of traditional medicine known as 'Ayurveda'. This study is
the first to prove that an enriched extract of the plant can be used as
a successful treatment.
The same authors have previously tested the safety of their remedy in
animal experiments. They say that, "In this study, the compound was
shown to have no major adverse effects in our osteoarthritis patients.
It is safe for human consumption and even for long-term use".
Journal reference:
Krishanu Sengupta, Krishnaraju V Alluri, Andey Rama Sathis, Simanchala
Mishra, Trimurtulu Golakoti, Kadainti VS Sarma, Dipak Dey and Siba P
Raychaudhuri. A double blind, randomized, placebo controlled
study of the efficacy and safety of 5-Loxin(R) for treatment of
osteoarthritis of the knee. Arthritis Research & Therapy,
BioMed Central (2008, July 31). Frankincense Provides Relief To
Arthritis Sufferers. ScienceDaily. Retrieved July 31, 2008,
from http://www.sciencedaily.com
/releases/2008/07/080729234300.htm
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